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Louisville a heavy favorite over Murray State

The Cardinals are expected to roll Thursday night.

COLLEGE FOOTBALL: SEP 01 Aflac Kickoff Game - Louisville vs Georgia Tech Photo by David J. Griffin/Icon Sportswire via Getty Images

After a thrilling 39-34 win over Georgia Tech in the Aflac Kickoff Game last Friday, Louisville is a heavy favorite to move to 2-0 on the 2023 season with a win over FCS opponent Murray State Thursday night at L&N Stadium.

According to DraftKings Sportsbook, the Cardinals are a 42.5-point favorite over the Racers.

Louisville is 7-2 straight up in its last nine games as a favorite. Included in that stretch is their season-opening victory six days ago.

Picked to finish 11th in the Missouri Valley Conference, Murray State is coming off of a 41-10 drubbing of Presbyterian in its season-opener. The Racers finished the 2022 season with a 2-9 record.

Louisville has won seven of its last nine games when playing as a favorite. The Cardinals have also won their last six meetings with Murray State.

Odds/lines subject to change. T&Cs apply. See for details.