Louisville has opened as a 10.5-point favorite for Wednesday evening's home game against Florida State.
The 12-5 Seminoles are coming off their biggest win of the season, a 69-62 victory over then-No. 13 Virginia on Sunday. They will bring a 2-3 ACC record with them into the Yum Center Wednesday.
Louisville has lost just once as a favorite this season, a 66-62 defeat at Clemson last Sunday when the Cards were favored to win by 7.5. Ken Pomeroy currently projects a 76-65 U of L victory over the Seminoles.