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Louisville is a 6-point underdog at Michigan State

For the first time in 2015-16, the Louisville basketball team will be an underdog when it takes the court inside the Breslin Student Events Center Wednesday night.

Michigan State opened as a 5.5-point favorite over the Cards in Vegas on Tuesday, a line which has since moved to -6. This will be the first time that U of L hasn't been favored to win a game since the last time they faced the Spartans, a game which took place in the Elite 8 of the 2015 NCAA Tournament. Tom Izzo's team was favored by 2.5 points for that tilt.

Louisville has been an underdog in just 27 games since 2011, and is 17-9-1 against the spread in those contests.