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Louisville Opens As A 3.5-Point Favorite Over Duke

Jamie Rhodes-USA TODAY Sports

The Cards may be ranked two spots behind Duke at the moment, but they will enter their showdown with the Blue Devils on Saturday as slight favorites.

Vegas has made U of L a 3.5-point favorite over Mike Krzyzewski's team, a line which has yet to move.

Louisville is 15-0 when favored this season, and 0-2 as an underdog.