Luke Winn on SI.com writes:

After picking Indiana in the preseason, a few things have changed my mind: The Cardinals' No. 1-ranked defense has been stingier than it was last season, allowing 0.802 adjusted points per possession --- and that's even with interior anchor Gorgui Dieng missing the past six games with a broken wrist. He'll be healthy well before March. Louisville's offense, which was mediocre in 2011-12, has been surprisingly strong due to the huge scoring-efficiency strides made by guards Russ Smith and Peyton Siva. And finally, I'm just not convinced that Indiana's interior D is national-title caliber, whereas Louisville is, without question, the best defensive team in the country.